1H MRS Reveals Major Changes in Brain Metabolites Induced by Human Pancreatic Cancer Xenografts

Author:Santosh Bharti  Paul Winnard Jr.  Yelena Mironchik  Marie-France Penet  Anirban Maitra  Zaver Bhujwalla  

Author Institution:Johns Hopkins University, School of Medicine  The University of Texas MD Anderson Cancer Center  

Session Type:Traditional Poster  

Session Date:Monday, 18 June 2018  

Session Time:08:15  

Session:Spectroscopy: NMR & Other  

Program Number:1339  

Presentation Time:

Room Number:Exhibition Hall 1336-1345  

Computer Number:

Automatic Myocardium Segmentation using Fully Conventional Network (FCN)

Author:Yan Wang  Peng Cao  Karen Ordovas  Jing Liu  

Author Institution:University of California, San Francisco  

Session Type:Traditional Poster  

Session Date:Thursday, 21 June 2018  

Session Time:08:00  

Session:Machine Learning for Tissue Segmentation & Classification  

Program Number:2734  

Presentation Time:

Room Number:Exhibition Hall 2726-2738  

Computer Number:

Carbon Nanodots as Diamagnetic CEST MRI Contrast Agents for Cell Labeling

Author:Jia Zhang  Minling Gao  Yue Yuan  Yuguo Li  Peter van Zijl  Mingyao Ying  Guanshu Liu  

Author Institution:Johns Hopkins University, School of Medicine  

Session Type:Power Pitch  

Session Date:Monday, 18 June 2018  

Session Time:13:45  

Session:Pitch: Molecular & Metabolic Imaging  

Program Number:0113  

Presentation Time:13:45  

Room Number:Power Pitch Theater A - Exhibition Hall  

Computer Number:

Carbon Nanodots as Diamagnetic CEST MRI Contrast Agents for Cell Labeling

Author:Jia Zhang  Minling Gao  Yue Yuan  Yuguo Li  Peter van Zijl  Mingyao Ying  Guanshu Liu  

Author Institution:Johns Hopkins University, School of Medicine  

Session Type:Electronic Power Pitch Poster  

Session Date:Monday, 18 June 2018  

Session Time:14:45  

Session:Poster: Molecular & Metabolic Imaging  

Program Number:0113  

Presentation Time:13:45  

Room Number:Power Pitch Theater A - Exhibition Hall  

Computer Number:Plasma 12  

Cerebral Blood Volume Mapping using Fourier-Transform based Velocity-Selective Saturation Pulse Trains

Author:Qin Qin  Yaoming Qu  Wenbo Li  Dapeng Liu  Taehoon Shin  Doris Lin  Peter van Zijl  Zhibo Wen  

Author Institution:Ewha Womans University  Johns Hopkins University  Zhujiang Hospital, Southern Medical University  

Session Type:Oral  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Arterial Spin Labeling  

Program Number:0307  

Presentation Time:17:15  

Room Number:W03/04  

Computer Number:

CEST MRI detection of Deoxycytidine Kinase activity using natural deoxycytidine

Author:Zheng Han  Jia Zhang  Yuguo Li  Jing Liu  Peter van Zijl  Guanshu Liu  

Author Institution:Johns Hopkins University  

Session Type:Combined Educational & Scientific Session  

Session Date:Wednesday, 20 June 2018  

Session Time:13:45  

Session:From Molecular Biomarker to Clinical Quantification  

Program Number:0781  

Presentation Time:15:25  

Room Number:S01  

Computer Number:

CEST MRI of 3-O-Methyl-D-Glucose uptake and accumulation in brain tumors

Clinical Feasibility Study of an Accelerated 3D Intracranial Magnetic Resonance Angiography Using Compressed-Sensing Algorithm

Author:Zhiyong Lin  Xiaodong Zhang  Ke Wang  Yuan Jiang  Xiaoyu Hu  Yong Huang  Shuai Ma  Yi Liu  Lina Zhu  Zhizheng Zhuo  Jing Liu  Xiaoying Wang  

Author Institution:Peking University First Hospital  Philips Healthcare  

Session Type:Oral  

Session Date:Tuesday, 19 June 2018  

Session Time:08:15  

Session:Application of Neurovascular Methods  

Program Number:0374  

Presentation Time:09:27  

Room Number:N02  

Computer Number:

Compressed-Sensing Accelerated 3-Dimensional Magnetic Resonance Imaging of Inner Ear: A Feasibility Study of Volunteer

Author:Yuan Jiang  Lina Zhu  Jing Liu  Xiaodong Zhang  Shuai Ma  Yi Liu  Zhiyong Lin  Ke Wang  Zhizheng Zhuo  Xiaoying Wang  

Author Institution:Peking University First Hospital  Philips Healthcare  

Session Type:Traditional Poster  

Session Date:Tuesday, 19 June 2018  

Session Time:16:15  

Session:Head & Neck  

Program Number:1961  

Presentation Time:

Room Number:Exhibition Hall 1961-1971  

Computer Number:

CORTICAL BONE VESSEL IDENTIFICATION ON CONTRAST-ENHANCED MR IMAGES

Author:Po-hung Wu  Jing Liu  Julio Carballido-Gamio  Misung Han  Roland Krug  Galateia Kazakia  

Author Institution:University of California - San Francisco  University of Colorado Denver - Anschutz Medical Campus  

Session Type:Oral  

Session Date:Thursday, 21 June 2018  

Session Time:15:30  

Session:Little Bones  

Program Number:1250  

Presentation Time:17:18  

Room Number:S05  

Computer Number:

COX-2 Alters the Metabolic Secretome in Triple Negative Human Breast Cancer Xenografts

Author:Santosh Bharti  Paul Winnard Jr.  Yelena Mironchik  Louis Dore-Savard  Balaji Kirshnamachary  Zaver Bhujwalla  

Author Institution:Johns Hopkins University, School of Medicine  McGill University Health Centre and RI-MUHC  

Session Type:Oral  

Session Date:Tuesday, 19 June 2018  

Session Time:16:15  

Session:Tumour Microenvironment  

Program Number:0635  

Presentation Time:17:39  

Room Number:W05/06  

Computer Number:

Detection of the accumulation of mannitol in rat brains using CEST MRI

Author:Jing Liu  Chengyan Chu  Lin Chen  Jia Zhang  Rohit Srivatava  Piotr Walczak  Jiadi Xu  Peter van Zijl  Miroslaw Janowski  Guanshu Liu  

Author Institution:The Johns Hopkins University School of Medicine  

Session Type:Electronic Poster  

Session Date:Wednesday, 20 June 2018  

Session Time:17:15  

Session:Advancements in CEST Methodology & Applications  

Program Number:5116  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 36  

Development of an 8-channel head array for MRI guided monkey ultrasound stimulation

The Effect of Altered Glucose Utilization on Dynamic GlucoCEST in a Preclinical Model of Glioblastoma

Author:Xiang Xu  Jing Liu  Jiadi Xu  Linda Knutsson  Huanling Liu  Yuguo Li  Bachchu Lal  John Laterra  Peter van Zijl  Kannie Chan  

Author Institution:Johns Hopkins University  Johns Hopkins University School of Medicine  

Session Type:Oral  

Session Date:Thursday, 21 June 2018  

Session Time:13:15  

Session:Predictive & Prognostic Cancer Imaging  

Program Number:1162  

Presentation Time:14:15  

Room Number:S04  

Computer Number:

Evaluation the Feasibility of Integrating Computer-aided Diagnosis as a Second Reader into Prostate Multiparametric MRI Diagnostic Process

Author:Lina Zhu  Ge Gao  Xiaoying Wang  Jing Liu  Rui Wang  Kai Zhao  Yuan Jiang  

Author Institution:Peking University First Hospital  

Session Type:Electronic Poster  

Session Date:Tuesday, 19 June 2018  

Session Time:16:15  

Session:Prostate 1: Clinical  

Program Number:4369  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 100  

Gene Expression Profiling to Understand the 1H MRS Characterization of the VEGF Metabolic Secretome from a Triple Negative Human Breast Cancer Xenograft

Author:Santosh Bharti  Balaji Kirshnamachary  Louis Dore-Savard  Brett Stark  Aleksander Popel  Zaver Bhujwalla  

Author Institution:Johns Hopkins University, School of Medicine  McGill University Health Centre and RI-MUHC  

Session Type:Traditional Poster  

Session Date:Monday, 18 June 2018  

Session Time:08:15  

Session:Spectroscopy: NMR & Other  

Program Number:1338  

Presentation Time:

Room Number:Exhibition Hall 1336-1345  

Computer Number:

High-resolution total Creatine mapping of the mouse brain at 11.7T using CEST

Author:Lin Chen  Zhiliang Wei  Xiang Xu  Yuguo Li  Shuhui Cai  Guanshu Liu  Hanzhang Lu  Peter Barker  Robert Weiss  Peter van Zijl  Jiadi Xu  

Author Institution:Johns Hopkins University  Xiamen University  

Session Type:Traditional Poster  

Session Date:Wednesday, 20 June 2018  

Session Time:08:15  

Session:CEST: Novel Methods & Applications  

Program Number:2248  

Presentation Time:

Room Number:Exhibition Hall 2222-2249  

Computer Number:

Imaging Blood Brain Barrier Disruption in Multiple Sclerosis using GlucoCEST MRI

Author:Xiang Xu  Pavan Bhargava  Linda Knutsson  Martin Pomper  Peter Calabresi  Peter van Zijl  

Author Institution:Johns Hopkins University  

Session Type:Electronic Poster  

Session Date:Wednesday, 20 June 2018  

Session Time:14:45  

Session:Blood Brain Barrier & CSF Flow  

Program Number:4923  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 57  

The Immune Checkpoint PD-L1 and Choline Kinase-a are inversely related in triple negative human breast cancer cells

Author:Jesús Pacheco-Torres  Marie-France Penet  Yelena Mironchik  Balaji Krishnamachary  Zaver Bhujwalla  

Author Institution:The Johns Hopkins University School of Medicine  

Session Type:Traditional Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Cancer Imaging  

Program Number:1533  

Presentation Time:

Room Number:Exhibition Hall 1509-1553  

Computer Number:

Impaired oxygen metabolism in the brain during visual stimulation in premanifest Huntington's Disease patients detected by 3D-TRIP MRI at 7T

Impaired oxygen metabolism in the brain during visual stimulation in premanifest Huntington's Disease patients detected by 3D-TRIP MRI at 7T

In Vivo iCEST MRI Detection of Zinc Depletion in an Orthotopic Prostate Cancer Mouse Model

Author:Yue Yuan  Chengyan Chu  Zhiliang Wei  Xiaolei Song  Jeff Bulte  

Author Institution:The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Molecular Imaging  

Program Number:3579  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 27  

Intracellular Assembly of Olsalazine Nanoparticles for CEST MR Imaging and Cancer Therapy

Joint estimation applied to attenuation correction for quiescent period respiratory gated PET data in PET/MR

Author:Sangtae Ahn  Jaewon Yang  Jing Liu  Youngho Seo  Thomas Hope  Peder Larson  Florian Wiesinger  

Author Institution:GE Global Research  GE Healthcare  University of California, San Francisco  

Session Type:Electronic Poster  

Session Date:Monday, 18 June 2018  

Session Time:17:15  

Session:MR/PET & Molecular Imaging  

Program Number:3686  

Presentation Time:

Room Number:Exhibition Hall  

Computer Number:Computer 14  

­Lentiviral shRNA-mediated targeting of GDPD5 and GDPD6 in Orthotopic Human Breast Cancer Xenograft Models: A Metabolomics Study

Author:Kanchan Sonkar  Marina Stukova  Caitlin Tressler  Balaji Krishnamachary  Zaver Bhujwalla  Kristine Glunde  

Author Institution:Johns Hopkins University School of Medicine  San Juan Bautista School of Medicine  

Session Type:Traditional Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Cancer Imaging  

Program Number:1530  

Presentation Time:

Room Number:Exhibition Hall 1509-1553  

Computer Number:

Liver metabolomic investigation of lentiviral targeting of GDPD5 and GDPD6 for breast cancer treatment in a preclinical model

Author:Kanchan Sonkar  Marina Stukova  Caitlin Tressler  Balaji Krishnamachary  Zaver Bhujwalla  Kristine Glunde  

Author Institution:Johns Hopkins University School of Medicine  San Juan Bautista School of Medicine  

Session Type:Traditional Poster  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Cancer Imaging  

Program Number:1547  

Presentation Time:

Room Number:Exhibition Hall 1509-1553  

Computer Number:

Mean Transit Time as a Marker of Vascular Change in Asymptomatic White Matter Disease

Author:Blake Dewey  Xiang Xu  Linda Knutsson  Amod Jog  Jerry Prince  Peter Barker  Peter van Zijl  Paul Nyquist  

Author Institution:Harvard Medical School  Johns Hopkins University  Lund University  

Session Type:Traditional Poster  

Session Date:Tuesday, 19 June 2018  

Session Time:16:15  

Session:Neurovascular Imaging Methods  

Program Number:1896  

Presentation Time:

Room Number:Exhibition Hall 1868-1902  

Computer Number:

Metabolic Consequences in the Heart and Skeletal Muscle of Human Pancreatic Cancer Xenograft Growth

Author:Santosh Bharti  Paul Winnard Jr.  Yelena Mironchik  Marie-France Penet  Zaver Bhujwalla  

Author Institution:Johns Hopkins University, School of Medicine  

Session Type:Traditional Poster  

Session Date:Monday, 18 June 2018  

Session Time:08:15  

Session:MRS Animal Studies  

Program Number:1365  

Presentation Time:

Room Number:Exhibition Hall 1361-1368  

Computer Number:

Metal-Free Contrast Agents

Author:Peter van Zijl  

Author Institution:

Session Type:Member-Initiated Symposium  

Session Date:Monday, 18 June 2018  

Session Time:16:15  

Session:Safety & Efficacy of Contrast Agents: State of the Art, Future Directions, & Alternative Approaches  

Program Number:

Presentation Time:17:40  

Room Number:N01  

Computer Number:

    MRI-derived myocardial strain in patients with mild cognitive impairment (MCI)

    Author:Heng Ma  Jun Yang  Haizhu Xie  Fang Wang  Xiao Xu  Wei Bai  Jing Liu  James Carr  Kai Lin  

    Author Institution:Northwestern University  Yuhuangding Hospital, Qingdao University School of Medicine  

    Session Type:Electronic Poster  

    Session Date:Monday, 18 June 2018  

    Session Time:13:45  

    Session:Cardiac Function & Myocardial Perfusion  

    Program Number:3328  

    Presentation Time:

    Room Number:Exhibition Hall  

    Computer Number:Computer 14  

    Multi-atlas tool for automated magnetic susceptibility quantification in brain nuclei

    Author:Andreia Faria  Lin Chen  Kwame Kutten  Can Ceritoglu  Ningdong Kang  Li Pan  Ye Qiao  Michael Miller  Susumu Mori  David Yousem  Peter van Zijl  Xu Li  

    Author Institution:Johns Hopkins University  Siemens Healthineers  

    Session Type:Oral  

    Session Date:Monday, 18 June 2018  

    Session Time:16:15  

    Session:Parameter Quantification  

    Program Number:0265  

    Presentation Time:16:51  

    Room Number:S03  

    Computer Number:

    NaSA-CEST: MR monitoring of brain inflammation using an aspirin metabolite as contrast agent

    Author:Xiaolei Song  Yanrong Chen  Chenwang Jin  Chengyan Chu  Irina Shats  Yuguo Li  Yue Yuan  Xiaowei He  Piotr Walzcak  Jeff Bulte  

    Author Institution:Johns Hopkins Univeristy  Northwest University  

    Session Type:Oral  

    Session Date:Tuesday, 19 June 2018  

    Session Time:08:15  

    Session:Novel CEST Methods in Cancer & Beyond  

    Program Number:0415  

    Presentation Time:09:39  

    Room Number:S05  

    Computer Number:

    A Novel MR Fingerprinting Approach for Fast Quantitative Chemical Exchange Saturation Transfer MRI Analysis by Subgrouping Proton Exchange Models (CEST-SPEM)

    Author:Hye-Young Heo  Shanshan Jiang  Peter van Zijl  Jinyuan Zhou  

    Author Institution:Johns Hopkins University  

    Session Type:Power Pitch  

    Session Date:Tuesday, 19 June 2018  

    Session Time:16:15  

    Session:Pitch: Advances in Contrast: MT, CEST & Perfusion  

    Program Number:0559  

    Presentation Time:16:15  

    Room Number:Power Pitch Theater B - Exhibition Hall  

    Computer Number:

    A Novel MR Fingerprinting Approach for Fast Quantitative Chemical Exchange Saturation Transfer MRI Analysis by Subgrouping Proton Exchange Models (CEST-SPEM)

    Author:Hye-Young Heo  Shanshan Jiang  Peter van Zijl  Jinyuan Zhou  

    Author Institution:Johns Hopkins University  

    Session Type:Electronic Power Pitch Poster  

    Session Date:Tuesday, 19 June 2018  

    Session Time:17:15  

    Session:Poster: Advances in Contrast: MT, CEST & Perfusion  

    Program Number:0559  

    Presentation Time:16:15  

    Room Number:Power Pitch Theater B - Exhibition Hall  

    Computer Number:Plasma 27  

    On Resonance Variable Delay Multiple Pulse (onVDMP) CEST MRI Detects Transient Lactate Depletion during Experimental Autoimmune Encephalomyelitis Progression

    Author:Aline Thomas  Jiadi Xu  Peter Calabresi  Peter van Zijl  Jeff Bulte  

    Author Institution:Johns Hopkins School of Medicine  Kennedy Krieger Institute  

    Session Type:Electronic Poster  

    Session Date:Monday, 18 June 2018  

    Session Time:08:15  

    Session:Emerging Methods  

    Program Number:3149  

    Presentation Time:

    Room Number:Exhibition Hall  

    Computer Number:Computer 75  

    On Resonance Variable Delay Multiple Pulse (onVDMP) CEST MRI for Monitoring Stem Cell Therapy in Experimental Autoimmune Encephalomyelitis

    Author:Aline Thomas  Jiadi Xu  Shen Li  Piotr Walczak  Peter Calabresi  Peter van Zijl  Jeff Bulte  

    Author Institution:Johns Hopkins School of Medicine  Kennedy Krieger Institute  

    Session Type:Electronic Poster  

    Session Date:Monday, 18 June 2018  

    Session Time:08:15  

    Session:Emerging Methods  

    Program Number:3150  

    Presentation Time:

    Room Number:Exhibition Hall  

    Computer Number:Computer 76  

    One Minute Free Breathing 3D Cardiac Cine MRI Using Data Clustering for Respiratory Self-Gating with Subject-Adaptive Gating Efficiency

    Author:Jing Liu  Peng Lai  Yan Wang  Zhaoying Wen  Karen Ordovas  

    Author Institution:GE Healthcare  University of California San Francisco  

    Session Type:Electronic Poster  

    Session Date:Wednesday, 20 June 2018  

    Session Time:14:45  

    Session:Motion & Beyond  

    Program Number:4900  

    Presentation Time:

    Room Number:Exhibition Hall  

    Computer Number:Computer 34  

    Oxygen extraction fraction is differentially affected in aging and Alzheimer’s disease: cross-sectional and longitudinal investigations in mice at 11.7T

    Author:Zhiliang Wei  Lin Chen  Zixuan Lin  Jiadi Xu  Siyuan Cheng  Zheyu Wang  Peter van Zijl  Hanzhang Lu  

    Author Institution:Johns Hopkins University  

    Session Type:Electronic Poster  

    Session Date:Monday, 18 June 2018  

    Session Time:17:15  

    Session:Alzheimer's Disease & Other Dementias  

    Program Number:3748  

    Presentation Time:

    Room Number:Exhibition Hall  

    Computer Number:Computer 76  

    Phase-contrast MRI for estimating global cerebral blood flow of mice at 11.7T: optimization and age-dependence

    Author:Zhiliang Wei  Lin Chen  Zixuan Lin  Jiadi Xu  Peter van Zijl  Hanzhang Lu  

    Author Institution:Johns Hopkins University  

    Session Type:Oral  

    Session Date:Thursday, 21 June 2018  

    Session Time:13:15  

    Session:Neurofluids & Glymphatic System  

    Program Number:1144  

    Presentation Time:14:39  

    Room Number:S02  

    Computer Number:

    Phenols as Diamagnetic T2-exchange Magnetic Resonance Imaging Contrast Agents

    Author:Jia Zhang  Yuguo Li  Stephania Slania  Nirbhay Yadav  Jing Liu  Rongfu Wang  Jianhua Zhang  Martin Pomper  Peter van Zijl  Xing Yang  Guanshu Liu  

    Author Institution:Johns Hopkins University  Johns Hopkins University, School of Medicine  Peking University First Hospital  

    Session Type:Electronic Poster  

    Session Date:Wednesday, 20 June 2018  

    Session Time:16:15  

    Session:Physiological Techniques  

    Program Number:5020  

    Presentation Time:

    Room Number:Exhibition Hall  

    Computer Number:Computer 35  

    Protein Aggregation in Mouse Brain with Alzheimer's Disease Revealed by Saturation Transfer MRI

    Author:Lin Chen  Zhiliang Wei  Kannie Chan  Shuhui Cai  Guanshu Liu  Hanzhang Lu  Philip Wong  Peter van Zijl  Tong Li  Jiadi Xu  

    Author Institution:Johns Hopkins University  Xiamen University  

    Session Type:Electronic Poster  

    Session Date:Wednesday, 20 June 2018  

    Session Time:14:45  

    Session:Neuroimaging: Animal Studies  

    Program Number:4984  

    Presentation Time:

    Room Number:Exhibition Hall  

    Computer Number:Computer 119  

    A Python-based MRI Reconstruction Toolbox, “MRIPY”, for Compressed Sensing, Parallel Imaging and Machine Learning

    Author:Peng Cao  Xucheng Zhu  Jing Liu  Yan Wang  Peder Larson  

    Author Institution:University of California at San Francisco  

    Session Type:Electronic Poster  

    Session Date:Monday, 18 June 2018  

    Session Time:14:45  

    Session:Image Reconstruction Potpourri  

    Program Number:3523  

    Presentation Time:

    Room Number:Exhibition Hall  

    Computer Number:Computer 91  

    Significant Metabolic Differences Between Benign Lipomatous Lesion and  Liposarcoma Identified by High-Resolution 1H and 31P MRS: A Pilot Study

    Author:Santosh Bharti  Brett Shannon  Adam Levin  Carol Morris  Laura Fayad  Zaver Bhujwalla  

    Author Institution:Johns Hopkins University, School of Medicine  

    Session Type:Traditional Poster  

    Session Date:Monday, 18 June 2018  

    Session Time:08:15  

    Session:MSK: Other  

    Program Number:1436  

    Presentation Time:

    Room Number:Exhibition Hall 1412-1437  

    Computer Number:

    Simultaneous Relaxometry and Segmentation of Human Brain through a Deep Neural Network

    Author:Peng Cao  Jing Liu  Shuyu Tang  Andrew Leynes  Peder Larson  

    Author Institution:University of California at San Francisco  

    Session Type:Power Pitch  

    Session Date:Wednesday, 20 June 2018  

    Session Time:08:15  

    Session:Pitch: Motion & Image Analysis Highlights  

    Program Number:0658  

    Presentation Time:08:15  

    Room Number:Power Pitch Theater B - Exhibition Hall  

    Computer Number:

    Simultaneous Relaxometry and Segmentation of Human Brain through a Deep Neural Network

    Author:Peng Cao  Jing Liu  Shuyu Tang  Andrew Leynes  Peder Larson  

    Author Institution:University of California at San Francisco  

    Session Type:Electronic Power Pitch Poster  

    Session Date:Wednesday, 20 June 2018  

    Session Time:09:15  

    Session:Poster: Motion & Image Analysis Highlights  

    Program Number:0658  

    Presentation Time:08:15  

    Room Number:Power Pitch Theater B - Exhibition Hall  

    Computer Number:Plasma 21